Health Nutrition & Diet 12 Health Benefits of Grapes—and Why They're a Nutritious Cheese Board Staple Grapes are crisp, juicy, refreshing—and remarkably nutritious. By Christina Manian, RDN Updated on August 07, 2024 Medically reviewed by Kristy Del Coro, MS, RDN, LDN Medically reviewed by Kristy Del Coro, MS, RDN, LDN Kristy Del Coro is a registered dietitian nutritionist, RDN, and professionally trained chef with more than 10 years of experience in the field of culinary nutrition. Her strong background in nutrition science, sustainable food systems, and culinary education makes her exceptionally qualified to write about food that is good for us and the planet—while not sacrificing flavor. Learn More Fact checked by Haley Mades Fact checked by Haley Mades Haley is a Wisconsin-based creative freelancer and recent graduate. She has worked as an editor, fact checker, and copywriter for various digital and print publications. Her most recent position was in academic publishing as a publicity and marketing assistant for the University of Wisconsin Press Our Fact-Checking Process Close Photo: ArtCookStudio/Getty Images With as many grape-based products available come an equally impressive amount of health benefits of grapes, including antioxidants and nutrients that support immune health, brain health, eye health, and more. It's no wonder why grapes are a cherished fruit for folks of almost every age. Grapes are a common finger food for kiddos, the star ingredient of adults’ favorite happy hour sip, a crisp and healthy midday snack, and a jewel of hearty chicken salads and cheese boards. We asked a nutrition expert for everything you need to know about grape nutrition so you can enjoy these bite-sized morsels even more, knowing how good they are for you. Amy Davis, RD, LDN, is a dietitian at FRESH Communications. Grape Nutrition Facts Grapes contain tons of vital vitamins and nutrients. For example, 1 cup of grapes (or about 151 grams) contains the following. Water - 122 gramsCalories - 104 kcalProtein - 1.09 grams (2.18% recommended daily value, or DV)Fat - 0.242 gramsCarbohydrates - 27.3 gramsFiber - 1.36 grams (4.86% DV)Sugars - 23.4 gramsCalcium - 15.1 milligrams (1.51% DV)Iron - 0.544 milligrams (3.02% DV)Magnesium - 10.6 milligrams (2.52% DV)Phosphorus - 30.2 milligrams (4.31% DV)Potassium - 288 milligrams (6.13% DV)Sodium - 3.02 milligramsZinc - 0.106 milligrams (0.96% DV)Copper - 0.192 milligrams (21.33% DV) Grapes also contain polyphenols like anthocyanins, flavanols, flavonols, and resveratrol. These naturally occurring compounds are found in plants and are known for their antioxidant properties and potential health benefits. Top Health Benefits of Grapes Beyond their mouthwatering flavor, maybe one of the most alluring aspects of these delectable fruits is the multitude of health benefits they offer. Here are some of the most noteworthy nutrients and health perks of grapes. 01 of 12 Boost Immunity If you’re looking to save up your sick days this year, grapes are a must-add to your grocery cart. These pops of flavor are loaded with vitamin C and plant compounds including resveratrol, quercetin, and anthocyanins. All of these micronutrients serve as antioxidants in the body, reducing inflammation and defending against disease-causing free radicals. In fact, one 2016 review of the current evidence found grapes to be super effective at preventing cancer, thanks to its unique nutrition profile. Resveratrol is a well-established broad spectrum anti-cancer agent, addressing dozens of varieties of this diagnosis, from brain and gastrointestinal cancers to thyroid and bone cancers. Quercetin equally measures up in the cancer department, helping to eliminate cancer cells through multiple mechanisms in their cellular growth and metabolism cycles. And, of course, we can’t forget anthocyanins which inhibit cancer cell growth, spread, and even reverse cancer cell drug resistance making them more sensitive to chemotherapy. 02 of 12 Enhance Vision While we have plant compounds at the top of mind, grapes also contain the phytonutrients lutein and zeaxanthin. These plant chemicals are actually plant pigments of the carotenoid family, well-known for boosting eye health (hello, carrots, pumpkin, and butternut squash!). Lutein and zeaxanthin are especially effective for eye health, because they’re the only two carotenoids that actually accumulate in the retina. This enables them to fight against age-related eye diseases including macular degeneration and cataracts. 03 of 12 Protect the Heart On the heart health front, grapes also seriously deliver as great sources of vitamin K, potassium, and, of course, plant compounds. “Grapes are high in vitamin K, which plays an important role in blood clotting,” explains Amy Davis, RD, LDN, dietitian at FRESH Communications. Healthy blood clotting is key not only to wound healing, but also to the prevention of clot-related cardiac events like heart attack and stroke. Meanwhile, “resveratrol can improve cholesterol levels and help lower blood pressure,” Davis adds. The impact resveratrol has on heart disease is well-documented in the research, as is quercetin. Studies have also shown that grape seed extract is particularly effective at treating high blood pressure. Managing cholesterol and blood pressure levels are paramount in avoiding the more dangerous implications of heart disease. 04 of 12 Support Bone Health Step aside dairy—grapes are here to give your bone-boosting powers a run for their money. When it comes to growing and maintaining strong bones, there are far more vitamins and minerals at play than just calcium, which gets all the attention. And you can have many of these in grapes. In fact, you’ll find vitamin K, vitamin C, copper, potassium, and magnesium in these ancient berries, all of which work together to support healthy bones and teeth. 05 of 12 Help Sleep If you have any sleep troubles whatsoever, grapes are here for you as an excellent natural source of melatonin, the primary hormone involved in regulating your sleep-wake cycle. This means they’re a great thing to munch on to support your ability to fall asleep and stay asleep, potentially addressing concerns and various sleep disorders. 06 of 12 Improve Metabolism These juicy fruits can also help regulate our blood sugars and support a healthy metabolism. One review of both animal and human studies found resveratrol to both lower insulin resistance and improve glycemic control (i.e. the body’s ability to manage its blood sugars effectively). A longitudinal study of over three million participants found that fruit consumption, especially grapes, was associated with lower risk of developing type 2 diabetes. 07 of 12 Boost Brain Health Our brains can also benefit from a daily serving of grapes, primarily due to their resveratrol, water, and vitamin B6 content. One review of the data found resveratrol to be linked with neuroprotective mechanisms that can help stave off neurodegenerative diseases, including Alzheimer’s. Quercetin found in grapes also boasts similar brain benefits. Meanwhile, a randomized control trial found that a grape extract supplement was linked with improved cognition in older adults. Grapes are also over 80 percent water, a vital element for brain health, aiding in brain cell communication, removing toxins and waste from the brain, and delivering nutrients to this all-important organ. All of these impacts equate to hydration’s capacity to improve memory and cognition while reducing the likelihood or severity of mood disorders, headaches, and brain-related diseases. The vitamin B6 found in grapes also supports healthy brain development. 08 of 12 Aid Red Blood Cell Production These clustered berries pack a punch when it comes to B vitamins, offering notable amounts of vitamin B6, thiamin, and riboflavin. While we already know that B6 supports the brain, it also plays a crucial role in the overall nervous system and immune system health. Meanwhile, thiamin (B1) is central to macronutrient metabolism, and riboflavin (B2) aids in red blood cell production, immune function, and overall growth and development. 09 of 12 Enhance Skin Grapes can even help improve and maintain your skin health. Resveratrol not only helps to reduce inflammation in the skin but also protects it from UV rays, wrinkles, and melanoma. This fantastic plant compound even helps to stimulate collagen production, further helping to slow signs of aging. The resveratrol, combined with the benzoyl peroxide in grapes, also attacks the bacteria that causes acne: Propionibacterium acnes. Resveratrol works to stop the formation of free radicals, which damage the skin cells. Benzoyl peroxide is an oxidant that kills acne-causing bacteria. Various different antioxidants that are found in grapes have also been shown to be beneficial for treating dermatological conditions like atopic dermatitis. 10 of 12 Increase Longevity Eating grapes can help promote longevity by inducing longevity genes (specific genes that are associated with promoting a longer life span and improving overall health). That's thanks to the resveratrol in grapes, which can increase life span. This doesn't mean that the more grapes you eat, the longer you'll live—but it does mean that it can't hurt. Longevity genes, when activated, enhance bodily functions and processes like DNA repair and stress resistance, both of which slow down aging and reduce your risk of age-related diseases. 11 of 12 Reduce Inflammation Grapes can help to reduce inflammation in the body. That's because they contain various polyphenols with antioxidative properties that work to reduce Nitric Oxide (NO) inactivation. 12 of 12 Improve Gut Health Grapes are largely made up of water, which makes them a very hydrating fruit that helps with digestion. Just one cup of grapes contains 122 grams of water. The combination of water, phytochemicals, fructose, and fiber all aid digestion and promote healthy bowel habits. More importantly, snacking on grapes can help relieve bloating and constipation. Grapes can also feel very filling. That's because just 1 cup contains 27.3 grams of carbohydrates, 1.09 grams of protein, and 1.36 grams of fiber. You can snack on them out of the carton or add them to your fruit bowls or yogurt; however you choose to eat them, they're a convenient snack. A Word on Wine, Grapes' Fermented Cousin It’s true that the health benefits associated with grapes, particularly in regards to their resveratrol content, still stand when it comes to wine. But since this powerful plant compound is found in the skin of grapes, red wine is the best option for reaping these grape health benefits during happy hour or dinner. That said, the alcohol content in wine arguably outweighs any health benefits associated with its micronutrient content. One glass of red wine per day (or less) is the maximum recommended amount for women, according to the 2015–2020 U.S. Dietary Guidelines. From promoting inflammation, especially in the gut, to increasing risk for multiple types of cancer, liver disease, mental health disorders, pancreatic illness, and heart disease, there are few areas of our health that booze harms. In fact, these risks are so pronounced that at the beginning of 2023, the World Health Organization (WHO) released a statement saying that all evidence points to no amount of alcohol being safe for our health. Grape Recipes Otherwise, grapes fit in with so many ingredients and recipes, both sweet and savory. The perfect snack on their own, straight from the fridge (after a rinse), grapes can be eaten fresh or frozen for a quick burst of energy. You can also add them to salads, oatmeals, chutneys, roasted vegetables, and baked goods. “They're also a great smoothie addition to sweeten without any added sugar,” Davis adds. No matter how you enjoy them, fresh or frozen, cooked or fermented, grapes are an undoubtedly nutritious addition to your healthy routine that the whole family will go wild for. For more inspiration check out these delicious, grape-studded recipes. Whole Roasted Cauliflower With Grapes and Feta Greg Dupree Roasted cauliflower pairs well with feta and seedless red or black grapes. They all cook together for a savory and sweet combination. GET THE RECIPE Green Gazpacho With Grapes, Honeydew, and Cucumber GREG DUPREE You've heard of gazpacho, but have you had a green gazpacho? This variation makes for a light summer soup. Top it with grapes, honeydew, and cucumber relish. GET THE RECIPE Spinach, Grape, and Coconut Smoothie Grant Cornett Seedless green grapes combine with coconut milk and baby spinach for an icy green smoothie. This smoothie is packed with vital vitamins and nutrients for a morning day-starter or afternoon pick-me-up. GET THE RECIPE Frequently Asked Questions What are the different types of grapes? These spherical fruits are technically berries, spawning from the perennial vining Vitis vinifera plant, whose woody arms can climb upwards of 12 feet in height. There are so many varieties of grapes to enjoy: green, blue, purple, red, pink, even cotton candy flavored. The flavor profiles of these types vary from tart to sweet. Some are perfect for snacking and cooking with, while others are best used in wine production. Are grapes safe to eat for everyone? Before you zoom to the supermarket for 10 bunches of grapes, there are a few additional nuggets of knowledge to keep in mind. "Since grapes are high in vitamin K, those taking blood thinners shouldn't overdo it on consumption," Davis explains. "Grapes can also be a choking hazard for kids, so they should be sliced into smaller pieces before serving to little ones.” When did people start eating grapes? Of all the fruits you can find, grapes may have one of the richest histories among them. Archaeological evidence shows that the cultivation of grapes (also known by their Latin name Vitis vinifera L.) dates back as early as 6500 BC in the Middle East, with cultural mythology believing these vining fruits to symbolize fertility and abundance. The popularity of grapes soon spread like wildfire across the globe, primarily driven by winemaking. How to Wash Grapes So They Stay Fresh Was this page helpful? Thanks for your feedback! Tell us why! Other Submit Sources Real Simple is committed to using high-quality, reputable sources, including peer-reviewed studies, to support the facts in our articles. Read our editorial guidelines to learn more about how we fact check our content for accuracy. "Grapes, red or green (European type, such as Thompson seedless), raw." U.S. Department of Agriculture. Deng, G. et al. "Biological Activities of Polyphenols from Grapes." International Journal of Molecular Sciences. Feb. 2010. Magrone T, Magrone M, Russo MA, et al. Recent advances on the anti-inflammatory and antioxidant properties of red grape polyphenols: in vitro and in vivo studies. Antioxidants (Basel). 2019;9(1):35. doi:10.3390/antiox9010035 Singh CK, Siddiqui IA, El-Abd S, et al. Combination chemoprevention with grape antioxidants. Mol Nutr Food Res. 2016;60(6):1406-1415. doi:10.1002/mnfr.201500945 Rauf A, Imran M, Butt MS, Nadeem M, et al. Resveratrol as an anti-cancer agent: A review. Crit Rev Food Sci Nutr. 2018;58(9):1428-1447. doi:10.1080/10408398.2016.1263597 Reyes-Farias M, Carrasco-Pozo C. The anti-cancer effect of quercetin: molecular implications in cancer metabolism. Int J Mol Sci. 2019;20(13):3177. doi:10.3390/ijms20133177 Lin BW, Gong CC, Song HF, et al. Effects of anthocyanins on the prevention and treatment of cancer. Br J Pharmacol. 2017;174(11):1226-1243. doi:10.1111/bph.13627 Mrowicka M, Mrowicki J, Kucharska E, Majsterek I. Lutein and zeaxanthin and their roles in age-related macular degeneration-neurodegenerative disease. Nutrients. 2022;14(4):827. doi:10.3390/nu14040827 American Society of Hematology, Blood clots. Accessed June 18, 2023. Salehi B, Machin L, Monzote L, et al. Therapeutic potential of quercetin: new insights and perspectives for human health. ACS Omega. 2020;5(20):11849-11872. doi:10.1021/acsomega.0c01818 Bonnefont-Rousselot D. Resveratrol and cardiovascular diseases. Nutrients. 2016;8(5):250. doi:10.3390/nu8050250 Zhang H, Liu S, Li L, et al. The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials. Medicine (Baltimore). 2016;95(33):e4247. doi:10.1097/MD.0000000000004247 Meng JF, Shi TC, Song S, et al. Melatonin in grapes and grape-related foodstuffs: A review. Food Chem. 2017;231:185-191. doi:10.1016/j.foodchem.2017.03.137 Xie Z, Chen F, Li WA, et al. A review of sleep disorders and melatonin. Neurol Res. 2017;39(6):559-565. doi:10.1080/01616412.2017.1315864 Szkudelski T, Szkudelska K. Resveratrol and diabetes: from animal to human studies. Biochim Biophys Acta. 2015;1852(6):1145-1154. doi:10.1016/j.bbadis.2014.10.013 Muraki I, Imamura F, Manson JE, et al. Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies [published correction appears in BMJ. 2013;347:f6935]. BMJ. 2013;347:f5001. doi:10.1136/bmj.f5001 Gomes BAQ, Silva JPB, Romeiro CFR, et al. Neuroprotective mechanisms of resveratrol in Alzheimer's Disease: role of SIRT1. Oxid Med Cell Longev. 2018;2018:8152373. doi:10.1155/2018/8152373 Khan H, Ullah H, Aschner M, et al. Neuroprotective effects of quercetin in Alzheimer's Disease. Biomolecules. 2019;10(1):59. doi:10.3390/biom10010059 Calapai G, Bonina F, Bonina A, et al. A randomized, double-blinded, clinical trial on effects of a Vitis vinifera extract on cognitive function in healthy older adults. Front Pharmacol. 2017;8:776. doi:10.3389/fphar.2017.00776 Pross N. Effects of dehydration on brain functioning: a life-span perspective. Ann Nutr Metab. 2017;70 Suppl 1:30-36. doi:10.1159/000463060 Kennedy DO. B Vitamins and the brain: mechanisms, dose and efficacy--a review. Nutrients. 2016;8(2):68. doi:10.3390/nu8020068 Hanna M, Jaqua E, Nguyen V, et al. B vitamins: functions and uses in medicine. Perm J. 2022;26(2):89-97. doi:10.7812/TPP/21.204 Wen S, Zhang J, Yang B, et al. Role of resveratrol in regulating cutaneous functions. Evid Based Complement Alternat Med. 2020;2020:2416837. doi:10.1155/2020/2416837 Ratz-Łyko A, Arct J. Resveratrol as an active ingredient for cosmetic and dermatological applications: a review. J Cosmet Laser Ther. 2019;21(2):84-90. doi:10.1080/14764172.2018.1469767 Champeau, R. "Antioxidant found in grapes uncorks new targets for acne treatment." UCLA Newsroom. Sep. 2014. Ahmad, N. et al. "Protective effects of dietary grape against atopic dermatitis-like skin lesions in NC/NgaTndCrlj mice." Frontiers in Immunology. Jan. 2023. Das, D. et al. "Longevity nutrients resveratrol, wines and grapes." Genes & Nutrition. March 2010. Gholami, A. et al. "Effect of grape polyphenols on selected inflammatory mediators: A systematic review and meta-analysis randomized clinical trials." EXCLI Journal. March 2020. Bae, S. "Diets for Constipation." Pediatric Gastroenteology, Hepatology & Nutrition. Dec. 2014. "Alcohol Use and Your Health." CDC. Bishehsari, F. et al. "Alcohol and Gut-Derived Inflammation." Alcohol Research Current Reviews. 2017. "No level of alcohol consumption is safe for our health." World Health Organization. Jan. 2023. Biddinger, K. et al. "Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease." JAMA. March 2022. University of Missouri Integrated Pest Management, Grapes: A brief history. Accessed June 17, 2023.